One Year Anniversary

Its been a year, take this minute to blow the dust out of your computers :)

On March 11, 2021, Canada marked the one year anniversary of WHO declaring COVID-19 a pandemic. We didn’t realize a year ago how long the path to recovery would take, or what it would look like, but we knew it would change everything. Our work had just begun…

On March 22, 2021, our Folding@Home team, “TEAM Equipe GOC”(Fold The North), will be celebrating our one year anniversary. This team started with just a few friends, mostly GC public servants, chatting online and seeking a way to help. This led to the idea, and to the formation of our folding team.

We wanted to help fight COVID-19. We wanted to contribute in the way we knew best. We needed something to focus on.

As of writing this, there are over 90 members of the team currently contributing their CPU and GPU processing power as part of our Fold the North initiative. This results in real money being spent by those who are contributing – money spent on electricity, internet connections, web hosting and hardware. Thank you for donating your time, your effort and your financial resources to making our efforts a success. Without your support, we would not have been able to accomplish all the amazing things we’ve done and all the communities we’ve reached.

I also want to thank all the people who’ve helped the team in other ways. The people who helped us spread the word, the people who presented with us, the people who helped share ideas and the people who lent their technical skills and gave hours of volunteering and support. Donating your time and passion is a crucial piece that made our team a success. We would be nothing without the people.

To all the others who helped us – all the people I’ve forgotten and to those who helped the helpers – I want to thank you too.

To underscore our team’s success, I want to share some of our year end statistics. We’re currently ranked 427 out of 225,494 teams – an unbelievable accomplishment. Thank you 

Some year-end stats on the team

As of March 15th, 2021. The team has generated:

The Spike Protein

What is the spike protein.

The spike of the SARS-CoV-2 virus (shown below) is one particularly appealing target for designing therapeutics to combat the COVID-19 disease. It is actually comprised of three identical proteins arranged in a circle. Many copies of the spike protrude from the surface of the virus, where they wait to encounter a protein on the surface of many human cells, called ACE2. Binding of a spike to ACE2 initiates a series of events that ultimately allow the virus to enter the human cell. Therefore, therapeutics that bind the spike in a manner that blocks its interaction with ACE2 could provide a valuable means to prevent infection.
Illustration of the Coronavirus S protein (Spike)

What does that look Like

How man vaccines are targetting the Spike protein

The table below is a snapshot in time , it has been copied from

You can search the table for either “S Protein” or Spike”. The table should return

  • 18 Vaccines targetting the “spike”
  • 10 Vaccines targetting “s proteins”

How did Folding @ Home help ?

The Folding @ Home users used their computing power to simulate the opening of the Spike Proteins “mouth”.

The three colors are the three proteins that come together to form the spike. Each is made of a linear chain of chemicals called amino acids. The ribbons trace out each chain. The transparent surface is the surface of the COVID-19 Demogorgon. The three proteins that make up the Demogorgon must spread apart to reveal the ACE2 binding site, which initiates infection by attaching to a protein called ACE2 on the surface of human cells. This movie captures part of that opening motion.